In a brain with a neurological disorder like epilepsy, synchronization between groups of neurons can grow to a dangerous extent when a collection of brain cells begins to emit excess electricity. Researchers used a mathematical model to explore the interplay between neurons that leads to these transitions in synchronization during the onset of seizures.
In a large-scale study of electronic health records investigators determined the prevalence of functional seizures and characterized comorbidities associated with them. Functional seizures are sudden attacks or spasms that look like epileptic seizures but do not have the aberrant brain electrical patterns of epilepsy. The research team confirmed associations […]
A new study shows that a protein -- called DUSP4 -- was increased in healthy brain tissue directly adjacent to epileptic tissue. The research suggests that boosting levels of DUSP4 could be a novel way of preventing or treating epilepsy.
People with generalized epilepsy who have seizures arising from both sides of the brain simultaneously, have a higher risk of obstructive sleep apnea (OSA) compared to patients who have focal epilepsy where seizures emanate from one area of the brain, according to a Rutgers study.
More frequent seizures during the menstrual cycle in women with genetic generalized epilepsy have been linked for the first time to drug-resistant epilepsy, when anti-seizure medications don't work, according to a new study that may help lead to tailored treatments.
Now a new study has found there is no difference in developmental and behavioral outcomes for children who have febrile seizures after vaccination, children who have febrile seizures not associated with vaccination and children who have never had a seizure.
Researchers have identified a critical new step in how brain cells function in people with one of the most common forms of epilepsy. This could lead to new treatment approaches for people with drug-resistant epilepsy.
A major international study has uncovered three molecules that have the potential to be developed into new drugs to treat epilepsy. The findings are an important step towards discovering new drugs for people with epilepsy whose seizures cannot be controlled with current treatments.
Marking a major milestone on the path to meeting the objectives of the NIH BRAIN initiative, researchers advance high-density electroencephalography (EEG) as the future paradigm for dynamic functional neuroimaging.
Unprovoked recurrent seizures are a serious problem affecting most patients who suffer from glioma, a primary brain tumor composed of malignant glial cells. Researchers tested the hypothesis that glioma-induces processes that renders a type of brain cells dysfunctional, perpetuating the imbalance between excitation and inhibition in tumor-associated epilepsy […]
Certain forms of epilepsy are accompanied by inflammation of important brain regions. Researchers have now identified a mechanism that explains this link. Their results may also pave the way to new therapeutic options in the medium term.
In patients with epilepsy, normal neurological activity becomes disrupted, causing debilitating seizures. Now, researchers report that they have found a potential new treatment for this disorder by turning to traditional Chinese medicine. Tests of extracts from plants used in these ancient remedies led the team to one compound, derived from a magnolia tree, […]
Roberto A. Molina,
Jorge G. Burneo,
Wim Van Paesschen,
Christian Erich Elger,
In recent years, researchers have begun using functional magnetic resonance imaging (fMRI) not just to better understand the neural bases of psychiatric illness, but also for experimental treatment of depression, ADHD, anxiety, PTSD, substance use disorder, and schizophrenia with real-time fMRI neurofeedback. But how well does it work?
By analysing the genome of tens of thousand people, a team has discovering similarities between the genetic bases of anorexia nervosa, bulimia nervosa or binge-eating disorder, and those of psychiatric disorders. Eating disorders differ in their genetic association with anthropometric traits. Thus, genetic predisposition to certain weight traits may be a dis […]
In one of largest and most comprehensive investigations of college students with ADHD ever conducted, new research confirms students with ADHD face significant challenges across all four years of college and predicts ways academic outcomes can be improved.
If depression is making it more difficult for some unemployed people to land a job, one type of therapy may help, research suggests. In a new study, 41% of unemployed or underemployed people undergoing cognitive behavioral therapy (CBT) found a new job or went from part- to full-time work by the end of the 16-week treatment for depression.
Loneliness is a risk factor associated with adolescents being drawn into compulsive internet use. The risk of compulsive use has grown in the coronavirus pandemic: loneliness has become increasingly prevalent among adolescents, who spend longer and longer periods of time online.
A new pair of studies make the case that early-life mental health problems can lead to physical diseases and advanced aging in adulthood. But because mental health conditions can appear early in life, the researchers say that investment in prompt mental health care could be used to prevent later diseases and reduce healthcare costs.
Scientists report the first evidence that, not short-term stress, like a series of tough college exams, rather chronic, unpredictable stress like that which erupts in our personal and professional lives, induces changes in the function of AgRP neurons that may contribute to depression.
Exposure to the bacteria that causes strep throat does not appear to make Tourette syndrome and other chronic tic disorders worse in children and teens, according to a new study. However, exposure was associated with increased symptoms of hyperactivity and impulsiveness.
Can long-term stress lead to heart attacks? Most people would probably answer in the affirmative, but the scientific evidence of this is scarce. A new study reveals that the levels of the stress hormone cortisol were increased in the months preceding a heart attack. The results suggest that long-term stress is a risk factor for heart attacks.
As families settle back into a new school year, sleep experts are reminding parents about the importance of teenagers getting enough sleep, cautioning them that insufficient sleep can negatively affect their mental health.
Feeding method and affectionate touch patterns in depressed and non-depressed mothers and babies as well as infant's EEG activity showed that mother-infant affectionate touch differed as a function of mood and feeding method (breastfeeding and bottle-feeding). Infants in the depressed and bottle-fed group reduced touch toward their mothers while breastf […]
A new study suggests that differences in the expression of gene transcripts - readouts copied from DNA that help maintain and build our cells - may hold the key to understanding how mental disorders with shared genetic risk factors result in different patterns of onset, symptoms, course of illness, and treatment responses.