In a brain with a neurological disorder like epilepsy, synchronization between groups of neurons can grow to a dangerous extent when a collection of brain cells begins to emit excess electricity. Researchers used a mathematical model to explore the interplay between neurons that leads to these transitions in synchronization during the onset of seizures.
In a large-scale study of electronic health records investigators determined the prevalence of functional seizures and characterized comorbidities associated with them. Functional seizures are sudden attacks or spasms that look like epileptic seizures but do not have the aberrant brain electrical patterns of epilepsy. The research team confirmed associations […]
A new study shows that a protein -- called DUSP4 -- was increased in healthy brain tissue directly adjacent to epileptic tissue. The research suggests that boosting levels of DUSP4 could be a novel way of preventing or treating epilepsy.
People with generalized epilepsy who have seizures arising from both sides of the brain simultaneously, have a higher risk of obstructive sleep apnea (OSA) compared to patients who have focal epilepsy where seizures emanate from one area of the brain, according to a Rutgers study.
More frequent seizures during the menstrual cycle in women with genetic generalized epilepsy have been linked for the first time to drug-resistant epilepsy, when anti-seizure medications don't work, according to a new study that may help lead to tailored treatments.
Now a new study has found there is no difference in developmental and behavioral outcomes for children who have febrile seizures after vaccination, children who have febrile seizures not associated with vaccination and children who have never had a seizure.
Researchers have identified a critical new step in how brain cells function in people with one of the most common forms of epilepsy. This could lead to new treatment approaches for people with drug-resistant epilepsy.
A major international study has uncovered three molecules that have the potential to be developed into new drugs to treat epilepsy. The findings are an important step towards discovering new drugs for people with epilepsy whose seizures cannot be controlled with current treatments.
Marking a major milestone on the path to meeting the objectives of the NIH BRAIN initiative, researchers advance high-density electroencephalography (EEG) as the future paradigm for dynamic functional neuroimaging.
Unprovoked recurrent seizures are a serious problem affecting most patients who suffer from glioma, a primary brain tumor composed of malignant glial cells. Researchers tested the hypothesis that glioma-induces processes that renders a type of brain cells dysfunctional, perpetuating the imbalance between excitation and inhibition in tumor-associated epilepsy […]
Robyn M. Busch,
Vanessa S. Almeida,
Cristiane S. Rocha,
Nam Suk Sim,
Jeong Ho Lee,
Se Hoon Kim,
Christopher A. Walsh,
Ryan N. Doan,
Katherine S. Morillo,
Thomas S. Jacques,
Harvey B. Sarnat,
Peter D. Galer,
Colin A. Ellis,
Rhys H. Thomas,
Peter N. Robinson,
Eric B. Segal,
James W. Wheless,
Gregory D. Cascino,
R. Edward Hogan,
Michael R. Sperling,
David F. Cook,
Adrian L. Rabinowicz,
The DIAZ.001.05 Study Group
Epilepsia, Volume 62, Issue 5, Page 1208-1219, May 2021.
Jessie De Ridder,
Anna C. Jansen,
Cyrille H. Ferrier,
David J. Kwiatkowski,
Floor E. Jansen,
the EPISTOP consortium,
L Emberti Gialloreti,
J. D. Mills,
J van Scheppingen
The relationship a dog has with its owner is related to its stress level. This is the conclusion of a newly published study. The results also suggest that the link between stress and the owner's personality traits differs between dog breeds.
Low levels of serotonin in the brain are seen as a possible cause of depression and many antidepressants act by blocking a protein that transports serotonin away from the nerve cells. A brain imaging study now shows that the average level of the serotonin transporter increased in a group of 17 individuals who recovered from depression after cognitive behavio […]
People who feel younger have a greater sense of well-being, better cognitive functioning, less inflammation, lower risk of hospitalization and even live longer than their older-feeling peers. A study suggests one potential reason for the link between subjective age and health: Feeling younger could help buffer middle-aged and older adults against the damagin […]
Young and middle-aged adults who reported severe psychological distress -- such as depression or anxiety -- after suffering a heart attack were more than twice as likely to suffer a second cardiac event within five years compared with those experiencing only mild distress, according to a new study.
Children born in December are almost twice as likely to be diagnosed with a learning disorder as those born in January in school districts with a December 31 cut-off date. ADHD was found not to affect the association between month of birth and the likelihood of a learning disability diagnosis.
Subtle differences in the shape of the brain that are present in adolescence are associated with the development of psychosis, according to an international team. The 'sobering' results were made using the largest study to date of brain scans in adolescents at risk for psychosis.
Despite increased use of repetitive transcranial magnetic stimulation in psychiatry, the rates at which patients respond to the therapy and experience remission of often-disabling symptoms have been modest at best. Now, a team of psychiatrists and biomedical engineers applied an emerging functional neuroimaging technology, known as diffuse optical tomography […]
A new study suggests that over the past 30 years, there has been little to no increase in the association between adolescents' technology engagement and mental health problems. The study also urges more transparent collaborations between academia and industry.
Psychedelic drugs have shown promise for treating neuropsychiatric disorders like depression and posttraumatic stress disorder. However, due to their hallucinatory side effects, some researchers are trying to identify drugs that could offer the benefits of psychedelics without causing hallucinations. Researchers now report they have identified one such drug […]
Childhood exposure to air pollution, such as nitrogen oxides and fine particulate matter, is a risk factor for mental illness at age 18. It is less of a factor than family history, but equal to lead, according to a new study. The finding comes from a cohort of 2,000 twins born in England and Wales in 1994-1995 and followed to young adulthood.
Astronauts who spend prolonged time alone in space face mental health stressors like loneliness, isolation and more. A psychologist developed the Mental Health Checklist, a self-reporting instrument for detecting mental health changes in isolated, confined, extreme environments. She's reporting results that show significant declines in positive emotions […]
Is it the difficulty of a task that determines whether or not students are stressed when working on it? Biologists working in biology didactics set out to find out the answers; to this end, the team used questionnaires and measured the heart rate in 209 test participants.
Researchers show that increased sensitivity in a specific region of the brain contributes to the development of anxiety and depression in response to real-life stress. Their study establishes an objective neurobiological measure for stress resilience in humans.
Researchers have shown that psilocybin -- the active chemical in 'magic mushrooms' -- still works its antidepressant-like actions, at least in mice, even when the psychedelic experience is blocked. The new findings suggest that psychedelic drugs work in multiple ways in the brain and it may be possible to deliver the fast-acting antidepressant ther […]
When the COVID-19 pandemic hit in early 2020, many families found themselves suddenly isolated together at home. A year later, new research has linked this period with a variety of large, detrimental effects on individuals' and families' well-being and functioning.