Now a new study has found there is no difference in developmental and behavioral outcomes for children who have febrile seizures after vaccination, children who have febrile seizures not associated with vaccination and children who have never had a seizure.
Researchers have identified a critical new step in how brain cells function in people with one of the most common forms of epilepsy. This could lead to new treatment approaches for people with drug-resistant epilepsy.
A major international study has uncovered three molecules that have the potential to be developed into new drugs to treat epilepsy. The findings are an important step towards discovering new drugs for people with epilepsy whose seizures cannot be controlled with current treatments.
Marking a major milestone on the path to meeting the objectives of the NIH BRAIN initiative, researchers advance high-density electroencephalography (EEG) as the future paradigm for dynamic functional neuroimaging.
Unprovoked recurrent seizures are a serious problem affecting most patients who suffer from glioma, a primary brain tumor composed of malignant glial cells. Researchers tested the hypothesis that glioma-induces processes that renders a type of brain cells dysfunctional, perpetuating the imbalance between excitation and inhibition in tumor-associated epilepsy […]
Certain forms of epilepsy are accompanied by inflammation of important brain regions. Researchers have now identified a mechanism that explains this link. Their results may also pave the way to new therapeutic options in the medium term.
In patients with epilepsy, normal neurological activity becomes disrupted, causing debilitating seizures. Now, researchers report that they have found a potential new treatment for this disorder by turning to traditional Chinese medicine. Tests of extracts from plants used in these ancient remedies led the team to one compound, derived from a magnolia tree, […]
In a study of epilepsy patients, researchers monitored the electrical activity of thousands of individual brain cells, called neurons, as patients took memory tests. They found that the firing patterns of the cells that occurred when patients learned a word pair were replayed fractions of a second before they successfully remembered the pair.
A research team has found that brains treated with certain drugs within a few days of an injury have a dramatically reduced risk of developing epilepsy later in life. The development of epilepsy is a major clinical complication after brain injury, and the disease can often take years to appear.
Children and teens with epilepsy who were treated with pharmaceutical cannabidiol (CBD) had much better seizure control than those who were treated with artisanal CBD, according to a preliminary study.
A team of neuroscientists have found, in animal models, that they can 'switch off' epileptic seizures. The findings provide the first evidence that while different types of seizures start in varied areas of the brain, they all can be controlled by targeting a very small set of neurons in the brain or their tendril-like neuronal axons.
Imagine not being able to drive, shower alone or even work because you are never quite sure when the next seizure will leave you incapacitated. Hope may be on the horizon for epilepsy patients who have had limited success with seizure drugs.
Scientists have developed a new therapeutic concept for the treatment of temporal lobe epilepsy. It represents a gene therapy capable of suppressing seizures at their site of origin on demand. Having been shown to be effective in an animal model, the new method will now be optimized for clinical use.
The risk of febrile convulsions increases with the child's fever, and children who suffer from repeated febrile convulsions during their first year of life have an increased risk of developing epilepsy and psychiatric disorders later in life. This is shown by a comprehensive register-based study. In the study, almost 76,000 Danish children who have been […]
An international team of researchers has developed new genetic-based epilepsy risk scores which may lay the foundation for a more personalized method of epilepsy diagnosis and treatment. This analysis is the largest study of epilepsy genetics to date, as well as the largest study of epilepsy using human samples.
In some forms of epilepsy, the function of certain ''brake cells'' in the brain is presumed to be disrupted. This may be one of the reasons why the electrical malfunction is able to spread from the point of origin across large parts of the brain. A current study points in this direction.
Awarded for the first time in 1963 to encourage epilepsy research in Germany, to date the MICHAEL PRIZE is one of the most highly regarded international awards for the best contribution to clinical and experimental research which promote further developments in epileptology.
Epilepsy & Behavior initiated a new category of paper entitled “Reflections on a Career in Epilepsy”. These contributions come from emeritus clinical and basic science researchers in the field of epilepsy who provide a brief autobiographical narrative of their careers which, collectively, begin to paint a mosaic of the recent history of advances in epile […]
There are few prospective studies on the causes of mortality in well-characterized cohorts with epilepsy and even fewer that have autopsy data that allow for reliable determination of SUDEP. We report causes of mortality and mortality rates in the Finnish cohort with childhood-onset epilepsy.
San Diego, CA, December 3, 2012 – In an editorial published in the current issue of the journal Epilepsy & Behavior, Epilepsy Foundation (EF) President and CEO Phil Gattone and Epilepsy Therapy Project (ETP) Chairman and Cofounder Warren Lammert discuss their personal journeys and rationale for the upcoming merger between two leading organizations in the […]
From 1st September 2012 Epilepsy & Behavior will stop accepting Case Reports for publication in the journal. From this date authors who submit to Epilepsy & Behavior will be offered a transfer or asked to resubmit their Case Reports to its new sister journal, Epilepsy & Behavior Case Reports.
Researchers found an unexpected spectrum of mental illnesses in patients with a rare gene mutation. These patients had a ''double hit'' condition that combined features and symptoms of fragile X syndrome and premutation disorder, in addition to a range of psychiatric symptoms. The findings revealed the need for clinicians to consider the […]
A new study shows that patient-derived adult stem cells can be used to model major depressive disorder and test how a patient may respond to medication and that fish oil, when tested in the model, created an antidepressant response.
Chronic stress is associated with the pathogenesis of psychological disorders such as depression. A study is the first to identify the role of a neuronal receptor that straddles the intersection between social stress, inflammation, and anxiety in rodent models of stress. Findings suggest the possibility of developing better medications to treat the consequen […]
A new survey conducted during the COVID-19 pandemic found a more-than-threefold increase in the percentage of US adults who reported symptoms of psychological distress -- from 3.9 percent in 2018 to 13.6 percent in April 2020.
Almost overnight, the rapid emergence of the COVID-19 pandemic in the United States and subsequent state and federal prevention measures dramatically altered daily behavior. A new study provides the first snapshot of the immediate impact of COVID-19 on Americans' stress levels, coping strategies, and adherence to public health guidelines.
The anaesthetic drug ketamine has been shown, in low doses, to have a rapid effect on difficult-to-treat depression. Researchers now report that they have identified a key target for the drug: specific serotonin receptors in the brain. Their findings give hope of new, effective antidepressants.