Over the past fifty years, there have been remarkable claims about the effects of Wolfgang Amadeus Mozart's music. Reports about alleged symptom-alleviating effects of listening to Mozart's Sonata KV448 in epilepsy attracted a lot of public attention. However, the empirical validity of the underlying scientific evidence has remained unclear. Now, p […]
Seizures can be predicted more than 30 minutes before onset in patients with temporal lobe epilepsy, opening the door to a therapy using electrodes that could be activated to prevent seizures from happening, according to new research.
Imagine slipping in and out of consciousness hundreds of times per day, staying awake the whole time but having no sense of awareness during these lapses. In children with absence epilepsy, these highly disruptive episodes are known as absence seizures. Absence seizures can be captured by abnormal rhythms on EEG recordings, but their neuronal cause has never […]
Researchers have discovered a specific genetic variant in SCN1A, the most common genetic epilepsy, that leads to an earlier onset of epilepsy, with clinical features distinct from other epilepsies. The researchers also identified a potentially effective treatment strategy.
Two new models could solve a problem that's long frustrated millions of people with epilepsy and the doctors who treat them: how to find precisely where seizures originate to treat exactly that part of the brain. By helping surgeons decide if and where to operate, the tools could help patients avoid risky and often-ineffective surgeries as well as prolo […]
Researchers have taken a key step toward improving the lives of patients with epilepsy by developing a sensor system for quickly testing their saliva to see if they have the correct level of anti-epileptic medicine in their system.
Temporal lobe epilepsy (TLE) is one of the most common types of epilepsy worldwide. Although symptomatic medications are available, one-third of TLE patients remain unresponsive to current treatment, so new drug targets are critically needed. Neuroscientist have recently identified and developed a new drug candidate that has potential for effectively treatin […]
Researchers propose a new method to differentiate signals from the epileptic focus from those recorded in other parts of the brain without the presence of an epileptic seizure. This technique may help detect epilepsy-induced features from these signals much quicker than conventional analysis techniques.
New research introduces a novel network analysis technology that uses minimally invasive resting state electrophysiological recordings to localize seizure onset brain regions and predict seizure outcomes in just 10 minutes.
Itay Tokatly Latzer,
Melissa L. DiBacco,
Henry H. C. Lee,
K. Michael Gibson,
Phillip L. Pearl
Madison M. Berl,
Jennifer I. Koop,
Donald J. Bearden,
Crystal M. Cooper,
Amanda M. Decrow,
Priscilla H. Duong,
David F. Marshall,
Kelly A. McNally,
Andrew E. Molnar,
Emily K. Olsen,
Kim E. Ono,
Kristina E. Patrick,
Brianna M. Paul,
Leigh N. Sepeta,
Rebecca L. H. Stilp,
Greta N. Wilkening,
M. Scott Perry,
the PERC Surgery Workgroup,
Allyson L. Alexander,
William D. Gaillard,
Chad Mac Manuel,
Michael J. McCormack,
Edward John Novotny,
Shilpa B. Reddy,
Erin Fedak Romanowski,
Eli J. Cornblath,
Simon S. Keller,
Russell T. Shinohara,
Joel M. Stein,
Kathryn A. Davis
New research finds that simply anticipating stress related to political elections causes adverse physical health effects. However, the study also finds there is something people can do to mitigate those negative health effects.
Researchers have found that adolescents who report strong relationships with their parents have better long-term health outcomes. Study findings suggest that investments in improving parent--adolescent relationships could help improve general health, mental health and sexual, health while also reducing substance use in young adulthood.
In experiments with mice and humans, a team led by Johns Hopkins Medicine researchers says it has identified a particular intestinal immune cell that impacts the gut microbiome, which in turn may affect brain functions linked to stress-induced disorders such as depression. Targeting changes mediated by these immune cells in the gut, with drugs or other thera […]
The COVID-19 pandemic has had a long-lasting impact on adolescent mental health and substance use, according to a new population-based study based on survey responses from a sample of over 64,000 13- to 18-year-olds assessed prior to and up to two years into the pandemic.
A new study suggests the rise in mental health disorders in children and teens is attributed to a decline over decades in opportunities for them to play, roam and engage in activities independent of direct oversight and control by adults. Although well intended, adults' drive to guide and protect children has deprived them of the independence they need […]
Hunter-gatherers can help us understand the conditions that children may be psychologically adapted to because we lived as hunter-gatherers for 95% of our evolutionary history. And paying greater attention to hunter-gatherer childhoods may help economically developed countries improve education and wellbeing.
Researchers have successfully developed a blood test for anxiety. The test examines biomarkers that can help them objectively determine someone’s risk for developing anxiety, the severity of their current anxiety and which therapies would likely treat their anxiety the best.
For older adults with clinical depression that has not responded to standard treatments, adding the drug aripiprazole to an antidepressant they're already taking is more effective than switching from one antidepressant to another, according to a new multicenter study.
A new brain connection can explain how early-life stress and adversity trigger disrupted operation of the brain's reward circuit, offering a new therapeutic target for treating mental illness. Impaired function of this circuit is thought to underlie several major disorders, such as depression, substance abuse and excessive risk-taking.
Adverse childhood experiences in mothers can affect their children's mental and physical health, as researchers report. The study found that maltreatment during a mother's childhood is associated with a higher risk of health problems such as asthma, autism, and depression in the next generation. Early intervention to support affected mothers might […]
Researchers are calling for exercise to be a mainstay approach for managing depression as a new study shows that physical activity is 1.5 times more effective than counseling or the leading medications.
Teens and young adults who reduced their social media use by 50% for just a few weeks saw significant improvement in how they felt about both their weight and their overall appearance compared with peers who maintained consistent levels of social media use, according to new research.
A new study explores the interplay between the serotonin system and estradiol in the brain, showing that the central nervous system in patients with premenstrual dysphoric disorder (PMDD) seems to increase serotonin transporter density from the periovulatory phase (when estradiol levels are high) to premenstrual cycle phase (when both estradiol and progester […]
Psychostimulants interacting with the dopamine transporter are found in the therapy of neuro-psychiatric disorders, such as ADHD or depression, as well as on the illicit drug market. In order to better understand their exact mode of action and undesirable effects, a research team has been working on the question of why different substances in this group of s […]
'Put down' language is a key indicator of poor mental health in athletes, recent research shows. More than 400 athletes across a variety of sports, ages and levels of experience were questioned for the study by sports psychology experts.
There is a correlation between traffic noise and risk of developing tinnitus, researchers have found. They point to a vicious cycle involving stress reactions and sleep disturbance as a potential cause. If you live near a busy road, it may increase your stress levels and affect your sleep. When we are under stress and sleep poorly, we may be at a higher risk […]