In a large-scale study of electronic health records investigators determined the prevalence of functional seizures and characterized comorbidities associated with them. Functional seizures are sudden attacks or spasms that look like epileptic seizures but do not have the aberrant brain electrical patterns of epilepsy. The research team confirmed associations […]
A new study shows that a protein -- called DUSP4 -- was increased in healthy brain tissue directly adjacent to epileptic tissue. The research suggests that boosting levels of DUSP4 could be a novel way of preventing or treating epilepsy.
People with generalized epilepsy who have seizures arising from both sides of the brain simultaneously, have a higher risk of obstructive sleep apnea (OSA) compared to patients who have focal epilepsy where seizures emanate from one area of the brain, according to a Rutgers study.
More frequent seizures during the menstrual cycle in women with genetic generalized epilepsy have been linked for the first time to drug-resistant epilepsy, when anti-seizure medications don't work, according to a new study that may help lead to tailored treatments.
Now a new study has found there is no difference in developmental and behavioral outcomes for children who have febrile seizures after vaccination, children who have febrile seizures not associated with vaccination and children who have never had a seizure.
Researchers have identified a critical new step in how brain cells function in people with one of the most common forms of epilepsy. This could lead to new treatment approaches for people with drug-resistant epilepsy.
A major international study has uncovered three molecules that have the potential to be developed into new drugs to treat epilepsy. The findings are an important step towards discovering new drugs for people with epilepsy whose seizures cannot be controlled with current treatments.
Marking a major milestone on the path to meeting the objectives of the NIH BRAIN initiative, researchers advance high-density electroencephalography (EEG) as the future paradigm for dynamic functional neuroimaging.
Unprovoked recurrent seizures are a serious problem affecting most patients who suffer from glioma, a primary brain tumor composed of malignant glial cells. Researchers tested the hypothesis that glioma-induces processes that renders a type of brain cells dysfunctional, perpetuating the imbalance between excitation and inhibition in tumor-associated epilepsy […]
Certain forms of epilepsy are accompanied by inflammation of important brain regions. Researchers have now identified a mechanism that explains this link. Their results may also pave the way to new therapeutic options in the medium term.
In patients with epilepsy, normal neurological activity becomes disrupted, causing debilitating seizures. Now, researchers report that they have found a potential new treatment for this disorder by turning to traditional Chinese medicine. Tests of extracts from plants used in these ancient remedies led the team to one compound, derived from a magnolia tree, […]
In a study of epilepsy patients, researchers monitored the electrical activity of thousands of individual brain cells, called neurons, as patients took memory tests. They found that the firing patterns of the cells that occurred when patients learned a word pair were replayed fractions of a second before they successfully remembered the pair.
A research team has found that brains treated with certain drugs within a few days of an injury have a dramatically reduced risk of developing epilepsy later in life. The development of epilepsy is a major clinical complication after brain injury, and the disease can often take years to appear.
Children and teens with epilepsy who were treated with pharmaceutical cannabidiol (CBD) had much better seizure control than those who were treated with artisanal CBD, according to a preliminary study.
João P. S. A. S. de Souza,
Luciana R. Pimentel‐Silva,
Mateus H. Nogueira,
Clarissa L. Yasuda,
Brunno M. Campos,
Carmen De Caro,
Luigi Francesco Iannone,
Giovambattista De Sarro
Epilepsia, Volume 62, Issue 1, Page 41-50, January 2021.
Jillian L. Rosengard,
Daniel José Correa,
Aristea S. Galanopoulou,
Alan D. Legatt,
Solomon L. Moshé,
Epilepsia, Volume 62, Issue 1, Page 198-216, January 2021.
Zachary M. Grinspan,
Anup D. Patel,
Renée A. Shellhaas,
Anne T. Berg,
Erika T. Axeen,
David F. Clarke,
William D. Gaillard,
Howard P. Goodkin,
Juma S. Mbwana,
Lindsey A. Morgan,
Nilika S. Singhal,
Margaret M. Storey,
Elissa G. Yozawitz,
Nicholas S. Abend,
Mark P. Fitzgerald,
Sara E. Fridinger,
Shavonne L. Massey,
Marisa S. Prelack,
the Pediatric Epilepsy Learning Healthcare System
Epilepsia, Volume 62, Issue 1, Page 51-60, January 2021.
Jordan D. T. Engbers,
Tolulope T. Sajobi,
Karl Martin Klein,
Colin B. Josephson
While we wait for our turn to get vaccinated against SARS-CoV-2, we could -- and probably should -- use the time to make sure we bring our healthiest emotional and physical selves to the treatment, a new review of previous research suggests.
A new study suggests more than half of doctors, nurses, and emergency responders involved in COVID-19 care could be at risk for one or more mental health problems, including acute traumatic stress, depression, anxiety, problematic alcohol use, and insomnia. The researchers found that the risk of these mental health conditions was comparable to rates observed […]
Mindfulness courses can reduce anxiety, depression and stress and increase mental wellbeing within most but not all non-clinical settings, say a team of researchers. They also found that mindfulness may be no better than other practices aimed at improving mental health and wellbeing.
Religious people facing life crises rely on emotion-regulation strategies that psychologists also use, a new study finds. They look for positive ways of thinking about hardship, a practice known to psychologists as 'cognitive reappraisal.' They also tend to have confidence in their ability to cope with difficulty, a trait called 'coping self-e […]
The COVID-19 pandemic is impacting people's mental health. But what helps and hinders people in getting through a lockdown? A new study addressed this question using data from 78 countries across the world. The results hint at the pivots and hinges on which the individual's psyche rests in the pandemic.
Fiber is a commonly recommended part of a healthy diet. That's because it's good for your health in so many ways -- from weight management to reducing the risk of diabetes, heart disease, and some types of cancer. A new study also finds that it might be linked with a reduced risk of depression, especially in premenopausal women.
Repeated intravenous (IV) ketamine infusions significantly reduce symptom severity in individuals with chronic post-traumatic stress disorder (PTSD) and the improvement is rapid and maintained for several weeks afterwards, according to a new study.
The introduction of computer simulation to the identification of symptoms in children with attention deficit/hyperactivity disorder (ADHD) has potential to provide an additional objective tool to gauge the presence and severity of behavioral problems, researchers suggest.
Posttraumatic stress disorder (PTSD) is a complex psychiatric disorder brought on by physical and/or psychological trauma. How its symptoms, including anxiety, depression and cognitive disturbances arise remains incompletely understood and unpredictable. Treatments and outcomes could potentially be improved if doctors could better predict who would develop P […]
The more chaotic things get, the harder it is for people with clinical anxiety and/or depression to make sound decisions and to learn from their mistakes. On a positive note, overly anxious and depressed people's judgment can improve if they focus on what they get right, instead of what they get wrong, suggests a new study.
A post-mortem analysis of brain tissue from people who had been diagnosed with post-traumatic stress disorder (PTSD) may help explain enduring mysteries about the disorder, such as why women are more susceptible to it and whether a dampened immune system response plays a role in dealing with stress, a team has found.
Adapting a traditional endless runner video game and using a raccoon as the protagonist, researchers have developed a platform that allows the identification and evaluation of the degree of attention deficit hyperactivity disorder (ADHD) in children and adolescents.
Individuals with high ADHD-traits that do not meet the criteria for a diagnosis are less able to perform tasks involving attentional regulation or emotional control after a sleepless night than individuals with low ADHD-traits, a new study reports.