A new study shows that a protein -- called DUSP4 -- was increased in healthy brain tissue directly adjacent to epileptic tissue. The research suggests that boosting levels of DUSP4 could be a novel way of preventing or treating epilepsy.
People with generalized epilepsy who have seizures arising from both sides of the brain simultaneously, have a higher risk of obstructive sleep apnea (OSA) compared to patients who have focal epilepsy where seizures emanate from one area of the brain, according to a Rutgers study.
More frequent seizures during the menstrual cycle in women with genetic generalized epilepsy have been linked for the first time to drug-resistant epilepsy, when anti-seizure medications don't work, according to a new study that may help lead to tailored treatments.
Now a new study has found there is no difference in developmental and behavioral outcomes for children who have febrile seizures after vaccination, children who have febrile seizures not associated with vaccination and children who have never had a seizure.
Researchers have identified a critical new step in how brain cells function in people with one of the most common forms of epilepsy. This could lead to new treatment approaches for people with drug-resistant epilepsy.
A major international study has uncovered three molecules that have the potential to be developed into new drugs to treat epilepsy. The findings are an important step towards discovering new drugs for people with epilepsy whose seizures cannot be controlled with current treatments.
Marking a major milestone on the path to meeting the objectives of the NIH BRAIN initiative, researchers advance high-density electroencephalography (EEG) as the future paradigm for dynamic functional neuroimaging.
Unprovoked recurrent seizures are a serious problem affecting most patients who suffer from glioma, a primary brain tumor composed of malignant glial cells. Researchers tested the hypothesis that glioma-induces processes that renders a type of brain cells dysfunctional, perpetuating the imbalance between excitation and inhibition in tumor-associated epilepsy […]
Certain forms of epilepsy are accompanied by inflammation of important brain regions. Researchers have now identified a mechanism that explains this link. Their results may also pave the way to new therapeutic options in the medium term.
In patients with epilepsy, normal neurological activity becomes disrupted, causing debilitating seizures. Now, researchers report that they have found a potential new treatment for this disorder by turning to traditional Chinese medicine. Tests of extracts from plants used in these ancient remedies led the team to one compound, derived from a magnolia tree, […]
In a study of epilepsy patients, researchers monitored the electrical activity of thousands of individual brain cells, called neurons, as patients took memory tests. They found that the firing patterns of the cells that occurred when patients learned a word pair were replayed fractions of a second before they successfully remembered the pair.
A research team has found that brains treated with certain drugs within a few days of an injury have a dramatically reduced risk of developing epilepsy later in life. The development of epilepsy is a major clinical complication after brain injury, and the disease can often take years to appear.
Children and teens with epilepsy who were treated with pharmaceutical cannabidiol (CBD) had much better seizure control than those who were treated with artisanal CBD, according to a preliminary study.
A team of neuroscientists have found, in animal models, that they can 'switch off' epileptic seizures. The findings provide the first evidence that while different types of seizures start in varied areas of the brain, they all can be controlled by targeting a very small set of neurons in the brain or their tendril-like neuronal axons.
Imagine not being able to drive, shower alone or even work because you are never quite sure when the next seizure will leave you incapacitated. Hope may be on the horizon for epilepsy patients who have had limited success with seizure drugs.
Omar K. Siddiqi,
Christopher M. Bositis,
Igor J. Koralnik,
Harris A. Gelbard,
William H. Theodore,
Jason F. Okulicz,
Brent A. Johnson,
David R. Bearden,
Gretchen L Birbeck
Ingrid E. Scheffer,
Jacqueline French, on behalf of
the Human Epilepsy Project Co‐Investigators
A new study has found that anxiety and stress directly linked to COVID-19 could be causing a number of body image issues. The research, which involved 506 UK adults, found that worries linked to COVID-19 were associated with body dissatisfaction and a desire for thinness in women, and associated with body fat dissatisfaction and a desire for muscularity in m […]
Children who are later diagnosed with autism and/or attention deficit hyperactivity disorder visit doctors and hospitals more often in their first year of life than non-affected children, suggesting a potential new way to identify the conditions early.
New research suggests that conditions such as attention deficit hyperactivity syndrome (ADHD), bipolar disorder, and even aggressive behaviors may be linked with sugar intake, and that it may have an evolutionary basis.
A review of 39 randomized clinical trials has found that combining the use medication with psychoeducational therapy is more effective at preventing a recurrence of illness in people with bipolar disorder than medication alone.
Researchers showed that STAT3 plays an important role in the serotonergic system as a molecular mediator for controlling emotional reactivity, thereby establishing a mechanistic link between the immune system, serotonergic transmission and affective disorders such as depression.
One in four adults reported a change in alcohol use almost immediately after stay-at-home orders were issued: 14 percent reported drinking more alcohol and reported higher levels of stress and anxiety than those who did not drink and those whose use stayed the same. The 11 percent who decreased their drinking also had higher levels of stress and anxiety -- s […]
The findings of the study show that oxytocin produced in the BNST increases stress-induced social anxiety behaviors in mice. This may provide an explanation as to why oxytocin can sometimes have antisocial effects.
A new study of asylum seekers in Germany suggests that, among those with symptoms of depression, anxiety, or posttraumatic stress disorder (PTSD), few receive a diagnosis from the health care system, and of those diagnosed, many do not receive treatment.
Researchers have identified a protein in the brain that is important both for the function of the mood-regulating substance serotonin and for the release of stress hormones, at least in mice. The findings may have implications for the development of new drugs for depression and anxiety.
A mindfulness-based stress reduction course was found to benefit patients with chronic pain and depression, leading to significant improvement in participant perceptions of pain, mood and functional capacity, according to a new study. Most of the study respondents (89%) reported the program helped them find ways to better cope with their pain while 11% remai […]
Children who show addiction-like gaming signs are not any more susceptible to mental health problems than their non-gaming peers. Some even experience less anxiety than others, according to researchers.
Researchers have reported an increased mortality risk in adults with depression who initiated augmentation with newer antipsychotic medications compared to a control group that initiated augmentation with a second antidepressant.
Can't stop checking social media for the latest COVID-19 health information? You might want to take a break, according to researchers who discovered that excessive use of social media for COVID-19 health information is related to both depression and secondary trauma.
Long after a COVID-19 vaccination is developed and years after the coronavirus death toll is tallied, the impact on mental health will linger, continuing to inflict damage if not addressed, according to new research.
Navigating through life requires balancing emotion and reason, a feat accomplished by the brain region 'area 32' of the anterior cingulate cortex. The area maintains emotional equilibrium by relaying information between cognitive and emotional brain regions, according to new research.